Retatrutide dosing schedule
Human schedule
Retatrutide is a triple receptor agonist (GIP/GLP-1/glucagon) administered as a once-weekly subcutaneous injection in studies. The below is a generalized reference to the titration regimen from published phase 2 clinical trials.
This is a concise reference to regimens described for adults; it is not an individual prescription.
| Period / condition | Dose | Escalation |
|---|---|---|
| Start (weeks 1–4) | 2 mg once weekly subcutaneously | Starting dose |
| Titration (every 4 weeks) | 4 → 8 mg once weekly | Increase if needed |
| Study maximum | 12 mg once weekly | Maximum in this schedule |