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Semaglutide dosing schedule

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Human schedule

Semaglutide is administered subcutaneously once weekly. The following is a generalized reference drawn from published studies and clinical GLP-1 titration protocols.

This is a concise reference to regimens described for adults; it is not an individual prescription.

Period / conditionDoseEscalation
Weeks 1–40.25 mg weeklyStarting dose
Weeks 5–80.5 mg weeklyIncrease if tolerated
Weeks 9–161.0–1.7 mg weeklyGradual increase
From week 172.4 mg weeklyMaximum in this schedule