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Bioregulators & AntioxidantsGlutathione (reduced, GSH)Glutathione (GSH) is the endogenous thiol tripeptide γ-L-glutamyl-L-cysteinylglycine, the cell's principal low-molecular-weight antioxidant and redox buffer. As an RUO reagent it is used to study redox homeostasis, xenobiotic detoxification, enzyme kinetics, and cellular models of oxidative stress.Bioregulators & AntioxidantsPinealon (Glu-Asp-Arg, EDR) — a Khavinson short peptidePinealon is a synthetic Glu-Asp-Arg (EDR) tripeptide from the Khavinson family of short peptides, studied as a neurotropic bioregulator. In preclinical models EDR penetrates the cell nucleus, interacts site-specifically with double-stranded DNA and modulates gene expression while lowering reactive oxygen species. This monograph summarizes its chemistry, molecular mechanism and the published research record; for research use only (RUO).