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MIF-1 (Pro-Leu-Gly-NH₂, melanostatin): a tripeptide positive allosteric modulator of dopamine D2/D4 receptors
MIF-1 (Pro-Leu-Gly-NH₂) is an endogenous tripeptide, an oxytocin fragment and a positive allosteric modulator of dopamine D2/D4 receptors that crosses the blood–brain barrier. A referenced review of the mechanism, the “melanostatin” history and the early (limited) research in Parkinson's disease and depression.
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